Package | Dosage | Price | Price per Dose | |
---|---|---|---|---|
Dosage: 25mg | ||||
360 pill | 25mg | €114.71 | €0.32 | |
180 pill | 25mg | €66.41 | €0.37 | |
120 pill | 25mg | €48.29 | €0.41 | |
90 pill | 25mg | €40.53 | €0.45 | |
60 pill | 25mg | €26.73 | €0.46 | |
30 pill | 25mg | €14.65 | €0.47 | |
Dosage: 100mg | ||||
180 pill | 100mg | €151.80 | €0.85 | |
120 pill | 100mg | €113.85 | €0.95 | |
90 pill | 100mg | €93.15 | €1.04 | |
60 pill | 100mg | €62.96 | €1.05 | |
30 pill | 100mg | €36.22 | €1.22 |

Spironolactone Description
Overview of Spironolactone
Spironolactone is a medication commonly used in the treatment of various medical conditions related to fluid retention and hormonal imbalance. It falls under the category of potassium-sparing diuretics, which means it promotes the excretion of excess fluid from the body while conserving potassium levels. This dual action makes it a unique choice for specific health issues. Its primary use is to manage conditions such as heart failure, edema, and certain forms of hypertension. Additionally, it has a significant role in treating hormonal disorders, especially those related to excess androgens. Its effect on hormone levels makes it useful in treating conditions like acne and hirsutism in women.
Mechanism of Action
Spironolactone works by blocking the action of aldosterone, a hormone that causes the kidneys to retain sodium and water. By inhibiting aldosterone, it helps reduce water retention and lower blood pressure. It also blocks androgen receptors and inhibits androgen synthesis, which explains its effectiveness in hormonal treatments. This dual mechanism makes it effective not only as a diuretic but also in managing conditions caused by hormonal imbalances. Because of its influence on hormones, it can lead to specific side effects related to hormonal changes, especially in women.
Uses and Benefits
This medication is prescribed for various health issues. Its primary indications include treating edema associated with congestive heart failure, liver cirrhosis, and kidney disease. It is also used to control hypertension, especially in cases where patients do not respond well to other diuretics. Beyond its cardiovascular benefits, spironolactone is often used off-label for managing hormonal conditions. It effectively reduces symptoms like acne and excessive hair growth in women with polycystic ovary syndrome (PCOS). Many patients also find that it helps improve their overall quality of life by reducing fluid-related discomfort and hormonal symptoms.
Possible Side Effects
Like all medications, spironolactone can cause side effects. Commonly reported issues include dizziness, gastrointestinal disturbances, and headaches. Due to its hormonal effects, some women may experience breast tenderness, irregular menstrual cycles, or increased menstrual bleeding. Uncommon but serious side effects can include hyperkalemia, which is an elevated level of potassium in the blood. Elevated potassium levels can be dangerous and require regular monitoring. Patients should be aware of these potential risks and communicate any unusual symptoms to their healthcare provider promptly.
Precautions and Interactions
Before starting spironolactone, patients should inform their healthcare provider about any existing health conditions, especially kidney problems, liver disease, or electrolyte imbalances. This medication can interact with other drugs, such as ACE inhibitors, other diuretics, or potassium supplements, increasing the risk of hyperkalemia. It is essential to follow prescribed doses and attend regular medical checkups for blood tests. Pregnant and breastfeeding women should consult their doctor before using spironolactone, as it may affect fetal development or pass into breast milk.
Conclusion
Spironolactone is a versatile medication with significant benefits in managing cardiovascular, hormonal, and fluid-related conditions. Its ability to block aldosterone and hormones makes it uniquely effective in various treatments. However, it requires careful use and monitoring due to potential side effects and interactions. When used appropriately under medical supervision, it can greatly improve health outcomes for many patients. As with all medications, proper guidance ensures its safety and efficacy in achieving the desired therapeutic results.